Epidemiology for Canadian Students

Epidemiology for Canadian Students introduces students to the principles and methods of epidemiology and critical appraisal, all grounded within a Canadian context. This context is crucial--epidemiologic research in Canada most often uses data from Canadian registries, Canadian special purpose cohorts, provincial health administrators, national statistical agencies and other sources that will be important to Canadian students during their careers.

Dr. Scott Patten draws on more than 20 years’ experience teaching epidemiology to present core concepts in a conversational tone and pragmatic sequence. This introductory textbook is suitable for both undergraduate and graduate students, health professionals and trainees.

Table of Contents

Table of Contents
Cover 1
Contents 6
PART I FIRST PRINCIPLES OF EPIDEMIOLOGY 8
1 What is epidemiology? 9
2 Epidemiological reasoning 17
PART II FUNDAMENTAL DESCRIPTIVE PARAMETERS 28
3 Basic measures based on frequencies and rates 29
4 Specialized mortality rates and composite measures of disease burden 42
PART III VULNERABILITY TO ERROR OF DESCRIPTIVE STUDIES 58
5 Random error from sampling 59
6 Measurement error that leads to misclassification 72
7 Misclassification bias in descriptive studies 84
8 Selection error and selection bias in descriptive studies 91
9 Confounding in descriptive studies 102
PART IV STUDY DESIGNS AND THEIR VULNERABILITY TO ERROR 118
10 Cross-sectional studies 119
11 Case-control studies 132
12 Differential and nondifferential misclassification bias in analytical studies 151
13 Prospective cohort studies 158
14 Confounding and effect modification in analytical studies 171
15 Stratified analysis and regression modelling in analytical studies 187
16 Other study designs 202
17 Other measures of association in epidemiology 215
PART V EVALUATING EPIDEMIOLOGICAL STUDIES 222
18 Causal judgement in epidemiology 223
19 Steps in critical appraisal 233
Answers to questions 251
Glossary 271
References 282
Index 291